| 產(chǎn)品編號 | bs-1985R |
| 英文名稱 | MCP-2 Rabbit pAb |
| 中文名稱 | 單核細(xì)胞趨化蛋白2抗體(小鼠) |
| 別 名 | MCP2; CCL 8; CCL8; CCL8; CCL8_MOUSE; C-C motif chemokine 8; Chemokine CC Motif Ligand 8; Chemokine CC Motif Ligand 8; HC14; HC14; MCP-2; MCP-2(6-76); Monocyte chemoattractant protein 2; Monocyte Chemotactic Protein 2; Monocyte Chemotactic Protein 2; SCYA10; SCYA8; SCYA8; Small inducible cytokine A8 [Precursor]; Small-inducible cytokine A8. |
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Specific References (2) | bs-1985R has been referenced in 2 publications.
[IF=38.49] Nguyen, Khoa D., et al. "Circadian gene Bmal1 regulates diurnal oscillations of Ly6Chi inflammatory monocytes." Science 341.6153 (2013): 1483-1488. FCM ; Mouse.
[IF=4.59] Terao, Mika, et al. "Local Glucocorticoid Activation by 11β-Hydroxysteroid Dehydrogenase 1 in Keratinocytes: The Role in Hapten-Induced Dermatitis."The American Journal of Pathology (2016). IHC-P ; Mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 趨化因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Mouse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 9 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse MCP-2: 20-97/97 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Jul 2008]. Function: Chemotactic factor that attracts monocytes. This protein can bind heparin (By similarity). Subunit: Monomer or homodimer; in equilibrium (By similarity). Subcellular Location: Secreted. Similarity: Belongs to the intercrine beta (chemokine CC) family. Database links: Entrez Gene: 6355 Human Entrez Gene: 20307 Mouse Omim: 602283 Human SwissProt: P80075 Human SwissProt: Q9Z121 Mouse Unigene: 271387 Human Unigene: 42029 Mouse 生長因子和激素（ Growth Factor and Hormones） |
