| 產品編號 | bs-4054R |
| 英文名稱 | MAT2A Rabbit pAb |
| 中文名稱 | 蛋氨酸腺苷轉移酶抗體 |
| 別 名 | MAT2A AdoMet synthetase 2; AdoMet synthetase; AMS 2; AMS2; MAT 2A; MAT II; MATA 2; MATA2; MATII; Methionine adenosyltransferase 2; Methionine adenosyltransferase; Methionine adenosyltransferase II alpha; Methionine adenosyltransferase II; S adenosylmethionine synthetase gamma form; S adenosylmethionine synthetase isoform type 2; SAMS 2; SAMS2; METK1_HUMAN. |
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Specific References (2) | bs-4054R has been referenced in 2 publications.
[IF=4.966] Li Chen. et al. Activating transcription factor 4 regulates angiogenesis under lipid overload via methionine adenosyltransferase 2A‐mediated endothelial epigenetic alteration. Faseb J. 2021 Jun;35(6):e21612 IHC ; Mouse.
[IF=4.181] Chen et al. Metabolomic analysis reveals metabolic changes caused by bisphenol A in rats. (2014) Toxicol.Sci. 138:256-67 WB ; Rat.
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| 研究領域 | 細胞生物 免疫學 信號轉導 轉錄調節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Zebrafish,Chicken,Dog,Monkey) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 44 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Methionine adenosyltransferase: 31-130/395 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
S adenosylmethionine synthetase catalyzes the formation of S adenosylmethionine from methionine and ATP. In mammalian tissues, there are three distinct forms of AdoMet synthases designated as alpha, beta, and gamma. Alpha and beta are expressed only in adult liver, while gamma is widely distributed in extrahepatic tissues. Function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. Subunit: Homotetramer (MAT-I) or homodimer (MAT-III). Tissue Specificity: Expressed in liver. Post-translational modifications: S-nitrosylation of Cys-120 inactivates the enzyme (By similarity). DISEASE: Defects in MAT1A are the cause of methionine adenosyltransferase deficiency (MATD) [MIM:250850]; also called MAT I/III deficiency. MATD is an inborn error of metabolism resulting in isolated hypermethioninemia. Most patients have no clinical abnormalities, although some neurologic symptoms may be present in rare cases with severe loss of methionine adenosyltransferase activity. Similarity: Belongs to the AdoMet synthase family. SWISS: P31153 Gene ID: 4144 Database links: Entrez Gene: 459363 Chimpanzee Entrez Gene: 101865874 Cynomolgus Monkey Entrez Gene: 4144 Human Entrez Gene: 232087 Mouse Entrez Gene: 695362 Rhesus monkey Entrez Gene: 323329 Zebrafish Omim: 601468 Human SwissProt: Q4R924 Cynomolgus Monkey SwissProt: P31153 Human SwissProt: Q3THS6 Mouse SwissProt: Q5R5H1 Orangutan Unigene: 516157 Human Unigene: 29815 Mouse Unigene: 485037 Mouse Unigene: 144658 Rat Unigene: 41420 Rat |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
