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DLL4 Rabbit pAb (bs-5909R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-5909R
英文名稱 DLL4 Rabbit pAb
中文名稱 DeltaD抗體
別    名 deltaD; delta4; delta-like 4(Drosophila); delta-like 4 homolog(Drosophila); Drosophila delta homolog 4; delta-like 4 homolog; delta-like 4 protein; Aei; After eight; dld; DLL4_HUMAN; delta-like protein 4; Drosophila delta homolog 4; delta 4 precursor; delta 4; delta ligand 4; notch ligand delta-2; hdelta2; MGC126344; notch ligand DLL4.  
研究領域 免疫學  發(fā)育生物學  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Rat (predicted: Mouse,Pig,Cow,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 75 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DLL4: 551-650/685 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 DeltaD is one of the 4 members of the zebrafish Delta family of Notch ligands, important in the control of cell differentiation in many tissues. DeltaD acts as a ligand for Notch receptors and is involved in primary neurogenesis and somitogenesis. It can activate Notch receptors, thereby playing a key role in lateral inhibition, a process that prevents the immediate neighbors of each nascent neural cell from simultaneously embarking on neural differentiation. It is required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized.

Function:
Cell surface proteoglycan that bears heparan sulfate. Required for cell division patterning during post-embryonic development of the nervous system.

Subcellular Location:
Cell membrane.

Similarity:
Belongs to the glypican family.

SWISS:
Q9NR61

Gene ID:
54567

Database links:

Entrez Gene: 54567 Human

Entrez Gene: 54485 Mouse

Entrez Gene: 311332 Rat

Omim: 605185 Human

SwissProt: Q9NR61 Human

SwissProt: Q9JI71 Mouse

Unigene: 511076 Human

Unigene: 143719 Mouse



產(chǎn)品圖片
Sample: Lane 1: Human K562 cell Lysates Lane 2: Human THP-1 cell Lysates Lane 3: Human 293T cell Lysates Primary: Anti-DLL4 (bs-5909R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75kDa Observed band size: 75kDa
Sample: Lung (Rat) Lysate at 40 ug Primary: Anti-DLL4 (bs-5909R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75 kD Observed band size: 75 kD
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