產(chǎn)品編號 | bs-6635R |
英文名稱 | Elongin A Rabbit pAb |
中文名稱 | 轉(zhuǎn)錄延伸因子3/ TCEB3抗體 |
別 名 | Ela1; Elo A; EloA; ELOA1_HUMAN; y Elongin 110 kDa subunit; Elongin-A; ElonginA; RNA polymerase II transcription factor SIII subunit A1; SIII; SIII p110; TCEB 3; TCEB3; TCEB3A; Transcription elongation factor B(SIII) polypeptide 3(110kD); Transcription elongation factor B(SIII) polypeptide 3; Transcription elongation factor B alpha subunit; Transcription elongation factor B polypeptide 3. |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號 | |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Chicken,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 90 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TCEB3/Elongin A: 701-798/798 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Function: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Subunit: Heterotrimer of an A (A1, A2 or A3), B and C subunit. The C subunit mediates the binding of the elongin BC complex to subunit A. Subcellular Location: Nucleus (Probable). Similarity: Contains 1 F-box domain. Contains 1 TFIIS N-terminal domain. SWISS: Q14241 Gene ID: 6924 Database links: Entrez Gene: 6924 Human Entrez Gene: 27224 Mouse Omim: 600786 Human SwissProt: Q14241 Human SwissProt: Q8CB77 Mouse Unigene: 15535 Human Unigene: 621226 Human Unigene: 27663 Mouse Unigene: 37427 Rat |