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PCDHGA4 Rabbit pAb (bs-11144R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-11144R
英文名稱 PCDHGA4 Rabbit pAb
中文名稱 原鈣粘蛋白γA4抗體
別    名 PCDHGA4; PCDHGA 4; PCDHGA-4; PCDH gamma A4; Protocadherin gamma A4; PCDG4_HUMAN.  
研究領域 信號轉導  細胞粘附分子  細胞骨架  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 98 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHGA4: 91-190/931 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGA4 (Protocadherin gamma-A4) is a 931 amino acid that is one of 22 proteins encoded by the protocadherin gamma cluster. The protocadherein gamma cluster consists of three subfamilies (A, B and C) and PCDHGA4 is a member of the gamma subfamily A. PCDHGA4 is a type I transmembrane receptor containing six cadherin motifs and is expressed in the central nervous system where it localizes to synapses. Members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGA4 that are produced as a result of alternative splicing events.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location:
Cell membrane; Single pass type I membrane protein

Similarity:
Contains 6 cadherin domains.

SWISS:
Q9Y5G9

Gene ID:
56111

Database links:


Entrez Gene: 56111 Human

Entrez Gene: 93712 Mouse

Entrez Gene: 252894 Rat

UniProtKB/Swiss-Prot: Q9Y5G9.1



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