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GPR21 Rabbit pAb (bs-13524R)  
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產(chǎn)品編號(hào) bs-13524R
英文名稱(chēng) GPR21 Rabbit pAb
中文名稱(chēng) G蛋白偶聯(lián)受體21抗體
別    名 G protein coupled receptor 21; G protein coupled receptor gpr21; Gpr 21; Gpr21; Probable G protein coupled receptor 21; GPCR GPR21; GPR21_HUMAN.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human (predicted: Pig,Cow,Horse,Monkey)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 38 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G protein coupled receptor 21: 1-100/349 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR21 is a 349 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR1 family. The gene encoding GPR21 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9.

Function:
GPR21 (G protein-coupled receptor 21) is an orphan G protein-coupled receptor (GPCR) with an unknown ligand.

Subcellular Location:
Cell membrane: Multi-pass membrane protein.

SWISS:
Q99679

Gene ID:
2844

Database links:

Entrez Gene: 2844 Human

Entrez Gene: 519193 Cow

Omim: 601909 Human

SwissProt: Q99679 Human

Unigene: 731933 Human



產(chǎn)品圖片
Sample:MCF-7 (Human)cell Lysate at 40 ug Primary: Anti-GPR21(bs-13524R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 38kD Observed band size: 35kD
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