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human IL-10/PE (bsm-30229A-PE)  
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產品編號 bsm-30229A-PE
英文名稱 human IL-10/PE
中文名稱 PE標記人IL-10單克隆抗體
別    名 Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN.  
抗體來源 Rat
克隆類型 Monoclonal
克 隆 號 3B4
交叉反應
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 18kDa
檢測分子量 21
性    狀 Liquid
亞    型 Rat IgG2a, k
純化方法 Affinity purified by Protein G
緩 沖 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存條件 Store at 2-8℃. Protect from light. Avoid freezing.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]

SWISS:
P22301

Gene ID:
3586

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