| 產(chǎn)品編號 | bs-9696R-BF594 |
| 英文名稱 | Rabbit Anti-C20orf19/BF594 Conjugated antibody |
| 中文名稱 | BF594標(biāo)記的20號染色體開放閱讀框19抗體 |
| 別 名 | DKFZP586H021; HT013; KIZUNA; MGC102941; MGC141930; Uncharacterized protein C20orf19; KIZ_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 75kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIZUNA/C20orf19 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf19 gene product has been provisionally designated C20orf19 pending further characterization. Function: Centrosomal protein required for establishing a robustmitotic centrosome architecture that can endure the forces thatconverge on the centrosomes during spindle formation. Required forstabilizing the expanded pericentriolar material around thecentriole. Subunit: Interacts with AKAP9, CEP72, ODF2, PCNT and TUBGCP2. Subcellular Location: Cytoplasm, cytoskeleton, centrosome.Note=Localizes to centrosomes throughout the cell cycle. Aftercentrosome duplication, it usually remains associated only with themother centrosome, containing the older mature centriole andparticles surrounding it. During prophase, additional particlesaccumulate around both separating centrosomes. Does not accumulateat the microtubule minus ends, but instead localizes to thecentrosomes and centrosome-surrounding area in amicrotubule-independent and dependent manner, respectively. Post-translational modifications: Phosphorylation at Thr-379 by PLK1 is not needed forcentrosomal localization or pericentriolar material expansion butis indispensable for spindle-pole stabilization. Similarity: Belongs to the kizuna family. Database links: Entrez Gene: 55857 Human SwissProt: Q2M2Z5 Human Unigene: 187635 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
