| 產(chǎn)品編號(hào) | bs-2503R-Gold |
| 英文名稱 | Rabbit Anti-eEF1A1/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的翻譯延伸因子EF-1a抗體 |
| 別 名 | Elongation Factor 1, Alpha; EF1 Alpha; eukaryotic translation elongation factor 1 alpha 1; CCS3; eEF1A-1; EF-Tu; EF1A; Elongation factor Tu; GRAF-1EF; PTI1; elongation factor 1-alpha 1; EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; MGC125172; SI; Eef1a1; EF1A1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 50kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EF1 alpha |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: eEF1A1 is an isoform of the alpha subunit of the elongation factor 1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. It promotes the GTP dependent binding of aminoacyl tRNA to the A site of ribosomes during protein biosynthesis. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome (referenced from entrez gene and swissprot). Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Subcellular Location: Cytoplasm. Tissue Specificity: Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle Post-translational modifications: ISGylated. Similarity: Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. Database links: Entrez Gene: 1915 Human Entrez Gene: 13627 Mouse Omim: 130590 Human SwissProt: P68104 Human SwissProt: P10126 Mouse Unigene: 520703 Human Unigene: 535192 Human Unigene: 586423 Human Unigene: 695681 Human Unigene: 713109 Human Unigene: 138471 Mouse Unigene: 335315 Mouse Unigene: 360075 Mouse Unigene: 391071 Mouse Unigene: 468942 Mouse Unigene: 144660 Rat Unigene: 965 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肽鏈延長(zhǎng)因子1A-1(peptide elongation factor 1A-1,eEF1A-1)是真核細(xì)胞蛋白翻譯過(guò)程中肽鏈延長(zhǎng)復(fù)合物的重要構(gòu)成成分,具有調(diào)節(jié)蛋白合成及促發(fā)凋亡等多種作用. |
