| 產(chǎn)品編號 | bs-4054R-BF488 |
| 英文名稱 | Rabbit Anti-MAT2A/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的蛋氨酸腺苷轉(zhuǎn)移酶抗體 |
| 別 名 | MAT2A AdoMet synthetase 2; AdoMet synthetase; AMS 2; AMS2; MAT 2A; MAT II; MATA 2; MATA2; MATII; Methionine adenosyltransferase 2; Methionine adenosyltransferase; Methionine adenosyltransferase II alpha; Methionine adenosyltransferase II; S adenosylmethionine synthetase gamma form; S adenosylmethionine synthetase isoform type 2; SAMS 2; SAMS2; METK1_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Zebrafish, Monkey, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 44kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Methionine adenosyltransferase (31-80aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: S adenosylmethionine synthetase catalyzes the formation of S adenosylmethionine from methionine and ATP. In mammalian tissues, there are three distinct forms of AdoMet synthases designated as alpha, beta, and gamma. Alpha and beta are expressed only in adult liver, while gamma is widely distributed in extrahepatic tissues. Function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. Subunit: Homotetramer (MAT-I) or homodimer (MAT-III). Tissue Specificity: Expressed in liver. Post-translational modifications: S-nitrosylation of Cys-120 inactivates the enzyme (By similarity). DISEASE: Defects in MAT1A are the cause of methionine adenosyltransferase deficiency (MATD) [MIM:250850]; also called MAT I/III deficiency. MATD is an inborn error of metabolism resulting in isolated hypermethioninemia. Most patients have no clinical abnormalities, although some neurologic symptoms may be present in rare cases with severe loss of methionine adenosyltransferase activity. Similarity: Belongs to the AdoMet synthase family. Database links: Entrez Gene: 459363 Chimpanzee Entrez Gene: 101865874 Cynomolgus Monkey Entrez Gene: 4144 Human Entrez Gene: 232087 Mouse Entrez Gene: 695362 Rhesus monkey Entrez Gene: 323329 Zebrafish Omim: 601468 Human SwissProt: Q4R924 Cynomolgus Monkey SwissProt: P31153 Human SwissProt: Q3THS6 Mouse SwissProt: Q5R5H1 Orangutan Unigene: 516157 Human Unigene: 29815 Mouse Unigene: 485037 Mouse Unigene: 144658 Rat Unigene: 41420 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
