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Rabbit Anti-Resistin/Gold Conjugated antibody (bs-0795R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0795R-Gold
英文名稱 Rabbit Anti-Resistin/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的抵抗素抗體
別    名 Adipose tissue specific secretory factor; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; Cysteine rich secreted protein A12 alpha like 2; Cysteine rich secreted protein FIZZ3; FIZZ 3; FIZZ3; Found in inflammatory zone 3; HXCP 1; HXCP1; MGC126603; MGC126609; PRO1199; Resistin delta2; RETN 1; RETN; RETN1; RSTN; UNQ407; XCP 1; XCP1  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 心血管  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  激酶和磷酸酶  糖尿病  內(nèi)分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Mouse, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Resistin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. [provided by RefSeq]

Function:
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed only in fatty tissues.

Similarity:
Belongs to the resistin/FIZZ family.

Database links:

Entrez Gene: 56729 Human

Entrez Gene: 57264 Mouse

Omim: 605565 Human

SwissProt: Q9HD89 Human

SwissProt: Q99P87 Mouse

Unigene: 283091 Human

Unigene: 1181 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

抵抗素Resistin, 是一種肽激素,富含半胱氨酸的分泌蛋白, 由脂肪細(xì)胞分泌的多肽類激素,屬于RELM家族,也稱之為ADSF(脂肪組織特異性的分泌因子),抵抗素可能是肥胖和胰島素抵抗之間的重要鏈接。近期研究結(jié)果顯示,抵抗素 (Resistin)還是一種重要的脂肪組織旁分泌調(diào)質(zhì), 參與內(nèi)血管內(nèi)皮細(xì)胞功能穩(wěn)態(tài)的調(diào)節(jié), 在二型糖尿病心血管病變發(fā)生發(fā)展過程中發(fā)揮重要病理生理學(xué)作用.
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