| 產品編號 | bs-2034R-Gold |
| 英文名稱 | Rabbit Anti-CRIM1/Gold Conjugated antibody |
| 中文名稱 | 膠體金標記的富含半胱氨酸運動神經元蛋白1抗體 |
| 別 名 | Cysteine-rich motor neuron 1 protein; CRIM-1; Cysteine-rich repeat-containing protein S52; Processed cysteine-rich motor neuron 1protein; CRIM 1; CRIM1; Cysteine rich motor neuron 1 protein; Cysteine rich repeat containing protein S52; Cysteine rich transmembrane BMP regulator 1 (chordin like); Cysteine rich transmembrane BMP regulator 1; MGC138194; Processed cysteine rich motor neuron 1 protein; S52; CRIM1_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領域 | 心血管 細胞生物 染色質和核信號 神經生物學 信號轉導 血管內皮細胞 細胞骨架 細胞外基質 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse, Rat, (predicted: Human, ) |
| 產品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 110kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CRIM1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產品介紹 |
background: CRIM1 interacts with BMP4 (bone morphogenic protein 4) and BMP7 and modulates BMP activity by affecting their processing and delivery to the cell surface. By interacting with growth factors implicated in motor neuron differentiation and survival, it may play a role in CNS development. It may also play a role in capillary formation and maintenance during angiogenesis. Function: May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. Subcellular Location: Secreted and Cell membrane. Tissue Specificity: Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver and small intestine. Expressed in blood vessels (at protein level). Post-translational modifications: N-glycosylated. Similarity: Contains 4 antistasin-like domains. Contains 1 IGFBP N-terminal domain. Contains 6 VWFC domains. Database links: Entrez Gene: 51232 Human Entrez Gene: 50766 Mouse Omim: 606189 Human SwissProt: Q9NZV1 Human SwissProt: Q9JLL0 Mouse Unigene: 699247 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
