| 產(chǎn)品編號 | bs-8110R-HRP |
| 英文名稱 | Rabbit Anti-UMPS/HRP Conjugated antibody |
| 中文名稱 | 辣根過氧化物酶標(biāo)記的尿苷磷酸合成酶抗體 |
| 別 名 | ODC; Uridine 5-monophosphate synthase; OMPdecase; OPRT; OPRTase; Orotate phosphoribosyl transferase and orotidine 5' decarboxylase; Orotate phosphoribosyltransferase; Orotate phosphoribosyltransferase phosphoribosyltransferase; Orotidine 5' phosphate decarboxylase; Orotidine 5''-phosphate decarboxylase; RP11-71H17.9; UMP synthase; Umps; UMPS_HUMAN; Uridine 5' monophosphate synthase; Uridine monophosphate synthetase. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細胞生物 信號轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, Cynomolgus Monkey, Rhesus monkey) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 52kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human UMPS |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] Subunit: Homodimer. DISEASE: Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:258900]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies. Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. In the C-terminal section; belongs to the OMP decarboxylase family. Database links: Entrez Gene: 460644 Chimpanzee Entrez Gene: 101124432 Gorilla Entrez Gene: 100070386 Horse Entrez Gene: 7372 Human Entrez Gene: 22247 Mouse Entrez Gene: 100173867 Orangutan Entrez Gene: 715664 Rhesus monkey Omim: 613891 Human SwissProt: P11172 Human SwissProt: P13439 Mouse SwissProt: Q5R514 Orangutan Unigene: 2057 Human Unigene: 13145 Mouse Unigene: 466951 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
