| 產(chǎn)品編號(hào) | bs-0369M-Cy5 |
| 英文名稱 | Mouse Anti-Rabbit IgM antibody |
| 中文名稱 | Cy5標(biāo)記的小鼠抗兔IgM |
| 別 名 | Mouse Anti-Rabbit IgM (Cy5); Immunoglobulin M; |
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Specific References (3) | bs-0369M-Cy5 has been referenced in 3 publications.
[IF=7.7] Li, Lian, et al. "Time-staggered delivery of docetaxel and H1-S6A, F8A peptide for sequential dual-strike chemotherapy through tumor priming and nuclear targeting." Journal of Controlled Release (2016). IF(ICC) ; Rabbit.
[IF=6.196] Cheng He. et al. Crosstalk of renal cell carcinoma cells and tumor-associated macrophages aggravates tumor progression by modulating muscleblind-like protein 2/B-cell lymphoma 2/beclin 1-mediated autophagy. CYTOTHERAPY. 2022 Oct;: IF ; Human.
[IF=3.65] Guan, Shan, et al. "An in vitro investigation of a detachable fork-like structure as efficient nuclear-targeted sub-unit in A2780 cell cultures."International Journal of Pharmaceutics (2016). Rabbit.
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| 抗體來(lái)源 | Mouse |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rabbit |
| 產(chǎn)品應(yīng)用 | Flow-Cyt=1:100-1000,IF=1:100-1000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 狀 | Liquid |
| 濃 度 | 2.0 mg/ml |
| 免 疫 原 | Native Rabbit IgM |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol. |
| 保存條件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Immunoglobulin M (IgM) normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
